Welcome to the Partnerships in Prevention Science Institute (PPSI). We are dedicated to advancing prevention science to promote healthy and capable youth, adults, families, and communities. Our mission is to integrate science with practice through innovative research and strong community partnerships, creating lasting legacies of well-being.


Our Vision
At PPSI, we envision a world where prevention science fosters capable and healthy individuals and communities, contributing to legacies of well-being across generations. Our mission is to conduct cutting-edge research that promotes the healthy development of youth, adults, families, and communities. We achieve this through partnerships that bridge the gap between science and practical application, ensuring our findings lead to real-world impact.

Achievements
Over the past 25 years, PPSI and its collaborators have secured over $80 million in grants, primarily from the National Institutes of Health. Our initiatives have been praised for reducing substance abuse and promoting positive behaviors among high-risk youth.

Collaborations
Our work is built on a foundation of strong partnerships with communities, schools, and organizations, both nationally and internationally. These collaborations are crucial for translating research into practice and achieving sustainable public health outcomes.
Research Areas
At PPSI, our research spans a wide range of topics related to prevention science and promoting positive human development. Our multidisciplinary team of researchers and practitioners collaborate to advance knowledge and develop evidence-based solutions in the following key areas:

Our research is grounded in a comprehensive understanding of the complex factors that influence individual, family, and community well-being. By integrating diverse perspectives and methodologies, we strive to develop innovative and effective strategies that can be implemented in real-world settings to create lasting positive change.
Key Projects

An RCT of Family-Centered Ojibwe Substance Abuse Prevention
This is a multisite randomized controlled trial of a family-centered alcohol and drug prevention program for Anishinabe (Ojibwe) pre-adolescents aged 8-10 years. This program has been developed and adapted in partnership with multiple Anishinabe communities over a span of 13 years. The Bii-Zin-Da-De-Dah (BZDDD) (Listening to One Another) program was the first American Indian adaptation of the Iowa Strengthening Families Program.

Building Capacity for PROSPER Rx Implementation to Address the Opioid Epidemic in Rural Iowa
The ISU PROSPER Rx team is expanding and enhancing supports and tools for building and leveraging the capacity of Extension professionals, along with their state- and community-level partners, to move toward an evidence-based comprehensive community systems approach to addressing the opioid epidemic in underserved rural communities.

Rural Family and Community Drug Abuse Prevention Project (Project Family)
Initiated in 1993, it is a longitudinal efficacy study to evaluate two family-focused interventions, Guiding Good Choices and Strengthening Families Program: For Parents and Youth 10-14, designed to prevent adolescent substance abuse and other problem behaviors. Multimethod, multi-informant measurement procedures were employed for collecting data when participants were at 6th, 7th, 8th, 10th, and 12th grades.
Discover Our Impact
At PPSI, we are proud of our extensive portfolio of projects that aim to enhance public health and promote positive human development. Our projects range from innovative research initiatives to impactful community programs, all designed to make a difference.
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Highlights
1. PROSPER was selected as one of two Tier 1 Comprehensive Community Initiatives based on a comprehensive review of the scientific literature showing its positive impact on a range of child, youth, and family outcomes. Read more.
2. A November 2017 report on drug and alcohol abuse and suicide by non-partisan Trust for America’s Health champions PPSI’s PROSPER project for reducing drunkenness, smoking, substance abuse, and conduct behavior problems among high-risk youth. The reports lists PROSPER as an effective effort that could be scaled up to benefit most U.S. communities. Read more.
3. Learn how a research-proven program can help address the opioid crisis. Read more.
Get Involved
Join us in making a difference. Learn how you can support our mission through donations, volunteering, or becoming a partner. Together, we can create healthier and more capable communities.
Have questions or need more information? Reach out to us at:
- Email: ppsiinquiry@iastate.edu
- Phone: